ASB 14780 is a 4-phenoxy derivative that exhibits highly selective inhibition of cytosolic phospholipase A2alpha (cPLA2alpha), with an IC50 value as low as 20 nM. By inhibiting the production of pro-inflammatory mediators such as arachidonic acid, ASB 14780 effectively reduces TPA-induced ear edema and ovalbumin-induced asthma responses in vivo.
Molecular Weight:
582.7
Purity:
99.71%
CAS Number:
[1069046-00-9]
Formula:
C35H38N2O6
Target:
Phospholipase
T37842
T37842
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