ASB 14780 is a 4-phenoxy derivative that exhibits highly selective inhibition of cytosolic phospholipase A2alpha (cPLA2alpha), with an IC50 value as low as 20 nM. By inhibiting the production of pro-inflammatory mediators such as arachidonic acid, ASB 14780 effectively reduces TPA-induced ear edema and ovalbumin-induced asthma responses in vivo.
Molekulargewicht:
582.7
Reinheit:
99.71%
CAS Nummer:
[1069046-00-9]
Formel:
C35H38N2O6
Target-Kategorie:
Phospholipase
T37842
T37842
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
