MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-alpha converting enzyme (TACE) in a dose-dependent manner (IC50 = 0.54 µM). MMP-9 inhibitor I decreases TNF-alpha secretion stimulated by LPS in BV-2 microglial cells when used at concentrations of 50 and 100 µM.
Molecular Weight:
511.63
CAS Number:
[206549-55-5]
Formula:
C27H33N3O5S
Target:
MMP
T37726
T37726
* VAT and and shipping costs not included. Errors and price changes excepted
