IRAK4-IN-33, CAS [[2411497-72-6]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T214453
Supplier Catalog Number:
T214453
Alternative Catalog Number:
TGM-T214453-10MG,TGM-T214453-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
IRAK4-IN-33 (Compound 22) is a selective and potent orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) with an IC50 value of 0.36 nM. It effectively blocks pro-inflammatory signaling pathways mediated by IRAK4 and inhibits the release of TNFalpha and IFNalpha. Additionally, IRAK4-IN-33 demonstrates weak inhibition of the hERG channel (IC50 value greater than 30 µM). This compound is applicable in inflammation and immunology research, such as studies on rheumatoid arthritis.
Molecular Weight:
538.63
CAS Number:
[2411497-72-6]
Formula:
C27H26N10OS
Target:
IRAK|||TNF|||IFNAR
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