IRAK4-IN-33, CAS [[2411497-72-6]] Preis auf Anfrage
Artikelnummer:
TGM-T214453
Hersteller Artikelnummer:
T214453
Alternativnummer:
TGM-T214453-10MG,TGM-T214453-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
IRAK4-IN-33 (Compound 22) is a selective and potent orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) with an IC50 value of 0.36 nM. It effectively blocks pro-inflammatory signaling pathways mediated by IRAK4 and inhibits the release of TNFalpha and IFNalpha. Additionally, IRAK4-IN-33 demonstrates weak inhibition of the hERG channel (IC50 value greater than 30 µM). This compound is applicable in inflammation and immunology research, such as studies on rheumatoid arthritis.
Molekulargewicht:
538.63
CAS Nummer:
[2411497-72-6]
Formel:
C27H26N10OS
Target-Kategorie:
IRAK|||TNF|||IFNAR
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
