Tubulin/VEGFR-2-IN-2, CAS [[2882998-56-1]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T214354
Supplier Catalog Number:
T214354
Alternative Catalog Number:
TGM-T214354-10MG,TGM-T214354-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Tubulin/VEGFR-2-IN-2 is an orally active dual inhibitor of tubulin and VEGFR-2, with IC50 values of 3.27 µM and 0.09 µM, respectively. This compound exerts antitumor effects through multiple pathways, including enhancing reactive oxygen species (ROS) production, disrupting mitochondrial membrane potential, inducing apoptosis, and causing cell cycle arrest. Tubulin/VEGFR-2-IN-2 also demonstrates significant anti-angiogenic properties in vitro, effectively inhibiting endothelial cell migration, invasion, and tube formation. Furthermore, in vivo, it inhibits angiogenesis, tumor growth, and metastasis. Tubulin/VEGFR-2-IN-2 is applicable for research on non-small cell lung cancer, breast cancer, gastric cancer, and lymphoma.
Molecular Weight:
366.42
CAS Number:
[2882998-56-1]
Formula:
C20H22N4O3
Target:
VEGFR|||Apoptosis|||ROS|||Microtubule Associated
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