Tubulin/VEGFR-2-IN-2, CAS [[2882998-56-1]] Preis auf Anfrage
Artikelnummer:
TGM-T214354
Hersteller Artikelnummer:
T214354
Alternativnummer:
TGM-T214354-10MG,TGM-T214354-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Tubulin/VEGFR-2-IN-2 is an orally active dual inhibitor of tubulin and VEGFR-2, with IC50 values of 3.27 µM and 0.09 µM, respectively. This compound exerts antitumor effects through multiple pathways, including enhancing reactive oxygen species (ROS) production, disrupting mitochondrial membrane potential, inducing apoptosis, and causing cell cycle arrest. Tubulin/VEGFR-2-IN-2 also demonstrates significant anti-angiogenic properties in vitro, effectively inhibiting endothelial cell migration, invasion, and tube formation. Furthermore, in vivo, it inhibits angiogenesis, tumor growth, and metastasis. Tubulin/VEGFR-2-IN-2 is applicable for research on non-small cell lung cancer, breast cancer, gastric cancer, and lymphoma.
Molekulargewicht:
366.42
CAS Nummer:
[2882998-56-1]
Formel:
C20H22N4O3
Target-Kategorie:
VEGFR|||Apoptosis|||ROS|||Microtubule Associated
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
