CETP Antibody / Cholesteryl Ester Transfer Protein, Rabbit, Polyclonal
Biozol Catalog Number:
NSJ-R31127
Supplier Catalog Number:
R31127
Alternative Catalog Number:
NSJ-R31127
Manufacturer:
NSJ Bioreagents
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Immunogen:
An amino acid sequence from the C-terminus of human Cholesteryl Ester Transfer Protein Plasma (PRPDQQHSVAYTFEE) was used as the immunogen for this CETP antibody.
Cholesteryl Ester Transfer Protein Plasma, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I(Day et al., 1994). Sparkes et al.(1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al.(2000) attempted to develop a potent, specific inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein (HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits.
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Purity:
Antigen affinity
Form:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Antibody Type:
Primary Antibody
Application Dilute:
Western blot: 0.5-1ug/ml
Application Notes:
The stated application concentrations are suggested starting amounts. Titration of the CETP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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