CETP Antibody / Cholesteryl Ester Transfer Protein, Rabbit, Polyclonal

Artikelnummer: NSJ-R31127
Artikelname: CETP Antibody / Cholesteryl Ester Transfer Protein, Rabbit, Polyclonal
Artikelnummer: NSJ-R31127
Hersteller Artikelnummer: R31127
Alternativnummer: NSJ-R31127
Hersteller: NSJ Bioreagents
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human
Immunogen: An amino acid sequence from the C-terminus of human Cholesteryl Ester Transfer Protein Plasma (PRPDQQHSVAYTFEE) was used as the immunogen for this CETP antibody.
Cholesteryl Ester Transfer Protein Plasma, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I(Day et al., 1994). Sparkes et al.(1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al.(2000) attempted to develop a potent, specific inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein (HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits.
Klonalität: Polyclonal
UniProt: P11597
Puffer: Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reinheit: Antigen affinity
Formulierung: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Antibody Type: Primary Antibody
Application Verdünnung: Western blot: 0.5-1ug/ml
Anwendungsbeschreibung: The stated application concentrations are suggested starting amounts. Titration of the CETP antibody may be required due to differences in protocols and secondary/substrate sensitivity.