Recombinant Human Claudin-6 (CLDN6)-VLPs (Active)

Catalog Number: CSB-MP005508HU(A4)
Article Name: Recombinant Human Claudin-6 (CLDN6)-VLPs (Active)
Biozol Catalog Number: CSB-MP005508HU(A4)
Supplier Catalog Number: CSB-MP005508HU(A4)
Alternative Catalog Number: CSB-MP005508HU(A4)-1, CSB-MP005508HU(A4)-100, CSB-MP005508HU(A4)-20
Manufacturer: Cusabio
Category: Proteine/Peptide
Alternative Names: (Skullin)
Molecular Weight: 24.8 kDa
Tag: C-terminal 10xHis-tagged (This tag can be tested only under denaturing conditions)
UniProt: P56747
Buffer: Lyophilized from a 0.2 µm sterile filtered PBS, 6% Trehalose, pH 7.4.
Source: Mammalian cell
Expression System: 1-220aa
Purity: Greater than 95% as determined by SEC-HPLC.
Form: Lyophilized powder
Sequence: MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV
Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 at 2 µg/mL can bind Anti-CLDN6/9 recombinant antibody(CSB-RA005508MA1HU). The EC50 is 1.334-1.504 ng/mL.The VLPs (CSB-MP3838) is negative control.②Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 at 2 µg/mL can bind Anti-CLDN6 recombinant antibody(CSB-RA005508MA2HU). The EC50 is 2.920-3.812 ng/mL.The VLPs (CSB-MP3838) is negative control.3Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 at 2 µg/mL can bind Anti-CLDN6/9 recombinant antibody(CSB-RA005508MA3HU). The EC50 is 3.482-4.097 ng/mL.The VLPs (CSB-MP3838) is negative control.④Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 at 2 µg/mL can bind Anti-CLDN6 recombinant antibody(CSB-RA005508MA4HU). The EC50 is 2.866-3.739 ng/mL.The VLPs (CSB-MP3838) is negative control.
The presence of VLP-like structures was confirmed by TEM②Human CLDN6 Monoclonal Antibody (CSB-RA005508MA1HU) captured on Protein A Chip can bind Human CLDN6 Full Length VLP Protein with an affinity constant of 6.58 nM as detected by MetaSPR Assay (WeSPRTM 200).
CSB-MP005508HU(A4) is detected by Mouse anti-6*His monoclonal antibody.