MS78 is an AceTAC molecule that selectively recruits p300/CBP to acetylate the p53Y220C mutant. This action promotes TRAIL-mediated apoptosis genes and inhibits DNA damage response pathways, supporting its use in cancer research for both cellular and animal studies of p53-mutant tumors.
Molecular Weight:
1024.25
Formula:
C57H66FN9O6S
Target:
Others,MDM-2/p53,Histone Acetyltransferase
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