MS78 is an AceTAC molecule that selectively recruits p300/CBP to acetylate the p53Y220C mutant. This action promotes TRAIL-mediated apoptosis genes and inhibits DNA damage response pathways, supporting its use in cancer research for both cellular and animal studies of p53-mutant tumors.
Molekulargewicht:
1024.25
Formel:
C57H66FN9O6S
Target-Kategorie:
Others,MDM-2/p53,Histone Acetyltransferase
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten