This compound is a potent and selective dopamine D3 receptor antagonist (Ki=66 nM) based on a THPB scaffold. It blocks both G-protein and beta-arrestin signaling pathways, making it a useful research tool for studying D3 receptor function in substance use disorders and Parkinsons disease in both cellular and animal models.
Molecular Weight:
455.59
Formula:
C27H37NO5
Target:
Dopamine Receptor
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