This compound is a potent and selective dopamine D3 receptor antagonist (Ki=66 nM) based on a THPB scaffold. It blocks both G-protein and beta-arrestin signaling pathways, making it a useful research tool for studying D3 receptor function in substance use disorders and Parkinsons disease in both cellular and animal models.
Molekulargewicht:
455.59
Formel:
C27H37NO5
Target-Kategorie:
Dopamine Receptor
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
