IHMT-IDH1-053 is a potent and selective irreversible inhibitor of the IDH1 R132H mutant, covalently binding at Cys269. It effectively suppresses 2-HG production in cells and inhibits the proliferation of IDH1-mutant cancer models, including fibrosarcoma and AML cells, making it a valuable tool for oncology research.
Molecular Weight:
532.63
Formula:
C25H33FN6O4S
Target:
Isocitrate Dehydrogenase (IDH)
* VAT and and shipping costs not included. Errors and price changes excepted
