IHMT-IDH1-053 is a potent and selective irreversible inhibitor of the IDH1 R132H mutant, covalently binding at Cys269. It effectively suppresses 2-HG production in cells and inhibits the proliferation of IDH1-mutant cancer models, including fibrosarcoma and AML cells, making it a valuable tool for oncology research.
Molekulargewicht:
532.63
Formel:
C25H33FN6O4S
Target-Kategorie:
Isocitrate Dehydrogenase (IDH)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
