TNO155, CAS [[1801765-04-7]]
Catalog Number:
BYT-ORB1309000
Product Overview
Article Name:
TNO155, CAS [[1801765-04-7]]
Biozol Catalog Number:
BYT-ORB1309000
Supplier Catalog Number:
orb1309000
Alternative Catalog Number:
BYT-ORB1309000-1,BYT-ORB1309000-10,BYT-ORB1309000-100,BYT-ORB1309000-2,BYT-ORB1309000-25,BYT-ORB1309000-5,BYT-ORB1309000-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
Batoprotafib, BCS, Aberrant, allosteric, activation, CRC, Inhibitor, HNSCC, malignancy, EGFR-mutant, inhibit, NSCLC, TNO155, TNO-155, TNO 155, RTK-dependent, Phosphatase, SHP2, SHP-2
Product Description
TNO155 is a potent and selective small molecule inhibitor of the SHP2 (PTPN11) phosphatase, exhibiting an IC50 of 11 nM. It is widely used in cancer research to investigate oncogenic signaling pathways, demonstrating antitumor activity in both cellular assays and in vivo models.
Product Properties
Molecular Weight:
421.95
Purity:
>99.99% (May vary between batches)
CAS Number:
[1801765-04-7]
Formula:
C18H24ClN7OS
Target:
Phosphatase
Application Notes
Application Notes:
Solubility: DMSO:50 mg/mL (118.5 mM),10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (5.92 mM)
