TNO155, CAS [[1801765-04-7]]

Artikelnummer: BYT-ORB1309000
Artikelname: TNO155, CAS [[1801765-04-7]]
Artikelnummer: BYT-ORB1309000
Hersteller Artikelnummer: orb1309000
Alternativnummer: BYT-ORB1309000-1,BYT-ORB1309000-10,BYT-ORB1309000-100,BYT-ORB1309000-2,BYT-ORB1309000-25,BYT-ORB1309000-5,BYT-ORB1309000-50
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: Batoprotafib, BCS, Aberrant, allosteric, activation, CRC, Inhibitor, HNSCC, malignancy, EGFR-mutant, inhibit, NSCLC, TNO155, TNO-155, TNO 155, RTK-dependent, Phosphatase, SHP2, SHP-2
TNO155 is a potent and selective small molecule inhibitor of the SHP2 (PTPN11) phosphatase, exhibiting an IC50 of 11 nM. It is widely used in cancer research to investigate oncogenic signaling pathways, demonstrating antitumor activity in both cellular assays and in vivo models.
Molekulargewicht: 421.95
Reinheit: >99.99% (May vary between batches)
CAS Nummer: [1801765-04-7]
Formel: C18H24ClN7OS
Target-Kategorie: Phosphatase
Anwendungsbeschreibung: Solubility: DMSO:50 mg/mL (118.5 mM),10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (5.92 mM)