HIP1 Antibody

Catalog Number: ASB-OACA06585
Article Name: HIP1 Antibody
Biozol Catalog Number: ASB-OACA06585
Supplier Catalog Number: OACA06585
Alternative Catalog Number: ASB-OACA06585-100UL,ASB-OACA06585-50UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IHC, WB
Species Reactivity: Human
Immunogen: Recombinant Human Huntingtin-interacting protein 1 protein (410-690AA)
Conjugation: Unconjugated
Alternative Names: HIP-I,huntingtin-interacting protein 1,huntingtin-interacting protein I,ILWEQ,SHON,SHONbeta,SHONgamma.
Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11532990, PubMed:11577110, PubMed:11889126). Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner (By similarity). Regulates presynaptic nerve terminal activity (By similarity). Enhances androgen receptor (AR)-mediated transcription (PubMed:16027218). May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway (PubMed:11007801). Binds 3-phosphoinositides (via ENTH domain) (PubMed:14732715). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis (PubMed:14732715). May play a functional role in the cell filament networks (PubMed:18790740). May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors (PubMed:11007801, PubMed:12163454).
Clonality: Polyclonal
NCBI: 3092
Form: Liquid
Immunohistochemistry of paraffin-embedded human colorectal carcinoma at dilution 1:100
Immunohistochemistry of paraffin-embedded human placenta at dilution 1:100
Western blot
All lanes: HIP1 antibody at 4ug/ml+A549 whole cell lysate
Secondary