HIP1 Antibody
Artikelnummer:
ASB-OACA06585
- Bilder (3)
| Artikelname: | HIP1 Antibody |
| Artikelnummer: | ASB-OACA06585 |
| Hersteller Artikelnummer: | OACA06585 |
| Alternativnummer: | ASB-OACA06585-100UL,ASB-OACA06585-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant Human Huntingtin-interacting protein 1 protein (410-690AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | HIP-I,huntingtin-interacting protein 1,huntingtin-interacting protein I,ILWEQ,SHON,SHONbeta,SHONgamma. |
| Plays a role in clathrin-mediated endocytosis and trafficking (PubMed:11532990, PubMed:11577110, PubMed:11889126). Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner (By similarity). Regulates presynaptic nerve terminal activity (By similarity). Enhances androgen receptor (AR)-mediated transcription (PubMed:16027218). May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway (PubMed:11007801). Binds 3-phosphoinositides (via ENTH domain) (PubMed:14732715). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis (PubMed:14732715). May play a functional role in the cell filament networks (PubMed:18790740). May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors (PubMed:11007801, PubMed:12163454). |
| Klonalität: | Polyclonal |
| NCBI: | 3092 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human colorectal carcinoma at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human placenta at dilution 1:100 |
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Western blot All lanes: HIP1 antibody at 4ug/ml+A549 whole cell lysate Secondary |
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