MACROD1 Antibody - N-terminal region

Catalog Number: ASB-ARP68610_P050
Article Name: MACROD1 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP68610_P050
Supplier Catalog Number: ARP68610_P050
Alternative Catalog Number: ASB-ARP68610_P050-25UL,ASB-ARP68610_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MACROD1
Alternative Names: LRP16
MACROD1 deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. It plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen and may play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. It could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction and could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. MACROD1 enhances ESR1-mediated transcription activity.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 36kDa
NCBI: 28992
UniProt: Q9BQ69
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit
Target Name: MACROD1
Sample Type: Fetal Brain lysates
Antibody Dilution: 1.0ug/ml
Host: Rabbit
Target: MACROD1
Positive control (+): Human kidney (KI)
Negative control (-): Human liver (LI)
Antibody concentration: 1ug/ml
MACROD1 Antibody - N-terminal region (ARP68610_P050) in Human Fetal Brain using Western Blot