MACROD1 Antibody - N-terminal region
Artikelnummer:
ASB-ARP68610_P050
- Bilder (3)
| Artikelname: | MACROD1 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP68610_P050 |
| Hersteller Artikelnummer: | ARP68610_P050 |
| Alternativnummer: | ASB-ARP68610_P050-25UL,ASB-ARP68610_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N-terminal region of Human MACROD1 |
| Alternative Synonym: | LRP16 |
| MACROD1 deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. It plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen and may play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. It could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction and could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. MACROD1 enhances ESR1-mediated transcription activity. |
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Host: Rabbit Target Name: MACROD1 Sample Type: Fetal Brain lysates Antibody Dilution: 1.0ug/ml |
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Host: Rabbit Target: MACROD1 Positive control (+): Human kidney (KI) Negative control (-): Human liver (LI) Antibody concentration: 1ug/ml |
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MACROD1 Antibody - N-terminal region (ARP68610_P050) in Human Fetal Brain using Western Blot |
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