SORD Antibody - N-terminal region

Catalog Number: ASB-ARP61128_P050
Article Name: SORD Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP61128_P050
Supplier Catalog Number: ARP61128_P050
Alternative Catalog Number: ASB-ARP61128_P050-25UL,ASB-ARP61128_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SORD
Alternative Names: RDH, SDH, XDH, SORD1, SORDD, HEL-S-95n
Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 38kDa
NCBI: 6652
UniProt: Q00796
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-SORD antibody
Catalog Number: ARP61128
Formalin Fixed Paraffin Embedded Tissue: Human Adult Liver
Observed Staining: Cytoplasm in hepatocytes
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 a€'' 2.0 sec
WB Suggested Anti-SORD Antibody
Titration: 1.0 ug/ml
Positive Control: Hela Whole CellSORD is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
SORD antibody - N-terminal region (ARP61128_P050) in Human HeLa using Western Blot