The immunogen is a synthetic peptide directed towards the N terminal region of human SORD
Alternative Synonym:
RDH, SDH, XDH, SORD1, SORDD, HEL-S-95n
Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
WB Suggested Anti-SORD Antibody Titration: 1.0 ug/ml Positive Control: Hela Whole CellSORD is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
SORD antibody - N-terminal region (ARP61128_P050) in Human HeLa using Western Blot
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