CNMD Antibody - N-terminal region

Catalog Number: ASB-ARP44615_P050
Article Name: CNMD Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP44615_P050
Supplier Catalog Number: ARP44615_P050
Alternative Catalog Number: ASB-ARP44615_P050-25UL,ASB-ARP44615_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LECT1
Alternative Names: CHM1, CHM-I, LECT1, BRICD3, MYETS1
This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 37kDa
NCBI: 11061
UniProt: O75829
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-LECT1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysateLECT1 is supported by BioGPS gene expression data to be expressed in 721_B
Host: Rabbit
Target Name: LECT1
Sample Tissue: Human 786-0
Antibody Dilution: 1.0ug/ml
LECT1 antibody - N-terminal region (ARP44615_P050) in Human 786-0 using Western Blot