CNMD Antibody - N-terminal region

Artikelnummer: ASB-ARP44615_P050
Artikelname: CNMD Antibody - N-terminal region
Artikelnummer: ASB-ARP44615_P050
Hersteller Artikelnummer: ARP44615_P050
Alternativnummer: ASB-ARP44615_P050-25UL,ASB-ARP44615_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LECT1
Alternative Synonym: CHM1, CHM-I, LECT1, BRICD3, MYETS1
This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 37kDa
NCBI: 11061
UniProt: O75829
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-LECT1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysateLECT1 is supported by BioGPS gene expression data to be expressed in 721_B
Host: Rabbit
Target Name: LECT1
Sample Tissue: Human 786-0
Antibody Dilution: 1.0ug/ml
LECT1 antibody - N-terminal region (ARP44615_P050) in Human 786-0 using Western Blot