SLC5A7 Antibody - C-terminal region

Catalog Number: ASB-ARP44025_P050
Article Name: SLC5A7 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP44025_P050
Supplier Catalog Number: ARP44025_P050
Alternative Catalog Number: ASB-ARP44025_P050-25UL,ASB-ARP44025_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC5A7
Alternative Names: CHT, CHT1, CMS20, HMN7A
This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 63 kDa
NCBI: 60482
UniProt: Q9GZV3
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Host: Rabbit
Target Name: SLC5A7
Sample Type: ACHN Whole Cell lysates
Antibody Dilution: 1.0ug/ml
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 0.5 ug/mL of the antibody was used in this experiment. Two isoforms of SLC5A7 can be detected in these samples as indicated.
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