SLC5A7 Antibody - C-terminal region
Artikelnummer:
ASB-ARP44025_P050
- Bilder (3)
| Artikelname: | SLC5A7 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP44025_P050 |
| Hersteller Artikelnummer: | ARP44025_P050 |
| Alternativnummer: | ASB-ARP44025_P050-25UL,ASB-ARP44025_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C-terminal region of human SLC5A7 |
| Alternative Synonym: | CHT, CHT1, CMS20, HMN7A |
| This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. |
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Host: Rabbit Target Name: SLC5A7 Sample Type: ACHN Whole Cell lysates Antibody Dilution: 1.0ug/ml |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 0.5 ug/mL of the antibody was used in this experiment. Two isoforms of SLC5A7 can be detected in these samples as indicated. |
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