CLDN11 Antibody - C-terminal region

Catalog Number: ASB-ARP33628_P050
Article Name: CLDN11 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP33628_P050
Supplier Catalog Number: ARP33628_P050
Alternative Catalog Number: ASB-ARP33628_P050-25UL,ASB-ARP33628_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN11
Alternative Names: OSP, OTM
CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 22kDa
NCBI: 5010
UniProt: O75508
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunohistochemistry of formalin-fixed, paraffin-embedded human brain, cortex, white matter tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Human Muscle
WB Suggested Anti-CLDN11 Antibody Titration: 0.2-1 ug/ml
Positive Control: Transfected 293T
CLDN11 antibody - C-terminal region (ARP33628_P050) in Transfected 293T using Western Blot