CLDN11 Antibody - C-terminal region
Artikelnummer:
ASB-ARP33628_P050
- Bilder (4)
| Artikelname: | CLDN11 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP33628_P050 |
| Hersteller Artikelnummer: | ARP33628_P050 |
| Alternativnummer: | ASB-ARP33628_P050-25UL,ASB-ARP33628_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN11 |
| Alternative Synonym: | OSP, OTM |
| CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease. |
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Immunohistochemistry of formalin-fixed, paraffin-embedded human brain, cortex, white matter tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. |
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Human Muscle |
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WB Suggested Anti-CLDN11 Antibody Titration: 0.2-1 ug/ml Positive Control: Transfected 293T |
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CLDN11 antibody - C-terminal region (ARP33628_P050) in Transfected 293T using Western Blot |
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