ASCL1 Antibody - N-terminal region

Catalog Number: ASB-ARP32355_T100
Article Name: ASCL1 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP32355_T100
Supplier Catalog Number: ARP32355_T100
Alternative Catalog Number: ASB-ARP32355_T100-25UL,ASB-ARP32355_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASCL1
Alternative Names: ASH1, HASH1, MASH1, bHLHa46
ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5-CANNTG-3). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 25 kDa
NCBI: 429
UniProt: P50553
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 4 ug/mL of the antibody was used in this experiment.
Human kidney
WB Suggested Anti-ASCL1 Antibody Titration: 1.25ug/ml
Positive Control: Human Thymus
ASCL1 antibody - N-terminal region (ARP32355_T100) in Human Thymus using Western Blot