ASCL1 Antibody - N-terminal region

Artikelnummer: ASB-ARP32355_T100
Artikelname: ASCL1 Antibody - N-terminal region
Artikelnummer: ASB-ARP32355_T100
Hersteller Artikelnummer: ARP32355_T100
Alternativnummer: ASB-ARP32355_T100-25UL,ASB-ARP32355_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASCL1
Alternative Synonym: ASH1, HASH1, MASH1, bHLHa46
ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5-CANNTG-3). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 25 kDa
NCBI: 429
UniProt: P50553
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 4 ug/mL of the antibody was used in this experiment.
Human kidney
WB Suggested Anti-ASCL1 Antibody Titration: 1.25ug/ml
Positive Control: Human Thymus
ASCL1 antibody - N-terminal region (ARP32355_T100) in Human Thymus using Western Blot