FADD Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51203
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| Article Name: | FADD Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51203 |
| Supplier Catalog Number: | AP51203 |
| Alternative Catalog Number: | ABT-AP51203-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, ICC, IHC-P, WB |
| Species Reactivity: | Human |
| Alternative Names: | FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity, Protein FADD, FADD, MORT1 |
| Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. |
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