FADD Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP51203
Artikelname: FADD Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP51203
Hersteller Artikelnummer: AP51203
Alternativnummer: ABT-AP51203-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, ICC, IHC-P, WB
Spezies Reaktivität: Human
Alternative Synonym: FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity, Protein FADD, FADD, MORT1
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Klonalität: Polyclonal
NCBI: 8772
UniProt: Q13158