CHP2 Antibody, Rabbit, Polyclonal

Catalog Number: ABT-AP51087
Article Name: CHP2 Antibody, Rabbit, Polyclonal
Biozol Catalog Number: ABT-AP51087
Supplier Catalog Number: AP51087
Alternative Catalog Number: ABT-AP51087-100UL
Manufacturer: Abcepta
Host: Rabbit
Category: Antikörper
Application: ELISA, IP, WB
Species Reactivity: Human, Mouse, Rat
Alternative Names: Calcineurin B homologous protein 2, Hepatocellular carcinoma-associated antigen 520, CHP2, HCA520
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation- induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.
Clonality: Polyclonal
NCBI: 63928
UniProt: O43745