CHP2 Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AP51087
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| Artikelname: | CHP2 Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AP51087 |
| Hersteller Artikelnummer: | AP51087 |
| Alternativnummer: | ABT-AP51087-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, IP, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Alternative Synonym: | Calcineurin B homologous protein 2, Hepatocellular carcinoma-associated antigen 520, CHP2, HCA520 |
| Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation- induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. |
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