HP1 alpha Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP51050
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| Article Name: | HP1 alpha Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP51050 |
| Supplier Catalog Number: | AP51050 |
| Alternative Catalog Number: | ABT-AP51050-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, ICC, IHC-P, IP, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Alternative Names: | Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha, CBX5, HP1A |
| Component of heterochromatin that recognizes and binds histone H3 tails methylated at Lys-9 (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when Tyr-41 of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
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