HP1 alpha Antibody, Rabbit, Polyclonal
Artikelnummer:
ABT-AP51050
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| Artikelname: | HP1 alpha Antibody, Rabbit, Polyclonal |
| Artikelnummer: | ABT-AP51050 |
| Hersteller Artikelnummer: | AP51050 |
| Alternativnummer: | ABT-AP51050-100UL |
| Hersteller: | Abcepta |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, ICC, IHC-P, IP, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Alternative Synonym: | Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha, CBX5, HP1A |
| Component of heterochromatin that recognizes and binds histone H3 tails methylated at Lys-9 (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when Tyr-41 of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
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