API5 Antibody, Rabbit, Polyclonal
Catalog Number:
ABT-AP50983
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| Article Name: | API5 Antibody, Rabbit, Polyclonal |
| Biozol Catalog Number: | ABT-AP50983 |
| Supplier Catalog Number: | AP50983 |
| Alternative Catalog Number: | ABT-AP50983-100UL |
| Manufacturer: | Abcepta |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IHC-P, IP, WB |
| Species Reactivity: | Human |
| Alternative Names: | Apoptosis inhibitor 5, API-5, Antiapoptosis clone 11 protein, AAC-11, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2-interacting factor, FIF, Protein XAGL, API5 |
| Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. |
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