API5 Antibody, Rabbit, Polyclonal

Artikelnummer: ABT-AP50983
Artikelname: API5 Antibody, Rabbit, Polyclonal
Artikelnummer: ABT-AP50983
Hersteller Artikelnummer: AP50983
Alternativnummer: ABT-AP50983-100UL
Hersteller: Abcepta
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IHC-P, IP, WB
Spezies Reaktivität: Human
Alternative Synonym: Apoptosis inhibitor 5, API-5, Antiapoptosis clone 11 protein, AAC-11, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2-interacting factor, FIF, Protein XAGL, API5
Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Klonalität: Polyclonal
NCBI: 8539
UniProt: Q9BZZ5