TNG961 is a potent, highly selective, CRBN-dependent HBS1L (GSPT3) molecular chaperone inhibitor. By degrading HBS1L, TNG961 specifically disrupts protein homeostasis in FOCAD-deficient cancer cells, thereby inducing growth inhibition and cell death. TNG961 can be used in studies of FOCAD-deficient tumors.
Molekulargewicht:
539.57
Formel:
C28H24F3N3O3S
Target-Kategorie:
Molecular Glues
T217526
T217526
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
