Dihydroactinidiolide is an acetylcholinesterase (AchE) inhibitor with an IC50 of 34.03. Dihydroactinidiolide increases the levels of Nrf2 and HO-1, reduces intracellular levels of ROS, nitrite, lipid peroxidation and protein carbonylation, scavenges DPPH and NO free radicals, and exhibits metal ion chelating activity. Dihydroactinidiolide inhibits the self-aggregation of Abeta25-35 and suppresses cell apoptosis. Dihydroactinidiolide inhibits seed germination and seedling growth, and acts as a pheromone component in insects and mammals. Dihydroactinidiolide can be used in research related to Alzheimers disease[1][2][3].
Molekulargewicht:
180.24
Reinheit:
99.75
CAS Nummer:
[17092-92-1]
Formel:
C11H16O2
Target-Kategorie:
Amyloid-beta,Apoptosis,Bcl-2 Family,Caspase,Cholinesterase (ChE),Heme Oxygenase (HO),Keap1-Nrf2,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Natural Products
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