JAK/HDAC-IN-2 is a dual-targeting 2-amino-4-phenylaminopyrimidine compound that potently inhibits JAK1/2 and HDAC3/6 at nanomolar levels. It induces apoptosis, blocks histone deacetylation and STAT3 phosphorylation, showing robust antiproliferative effects in studies of hematologic cancers and solid tumor models.
Molekulargewicht:
570.7
Formel:
C28H38N6O5S
Target-Kategorie:
Apoptosis,HDAC,JAK
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
