Compound 114 is a dual D3 dopamine and mu-opioid receptor antagonist with K i values of 46.5 nM and 691 nM, respectively. Its MOR partial agonism provides analgesic potential, while D3R antagonism may mitigate abuse liability, supporting research in neuropharmacology and addiction studies.
Molekulargewicht:
420.38
Formel:
C22H27Cl2N3O
Target-Kategorie:
Dopamine Receptor,Opioid Receptor
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