Compound 121 is a dual D3 receptor antagonist (K i = 361 nM) and mu-opioid receptor antagonist/partial agonist (K i = 85.2 nM). This profile suggests utility in preclinical research for investigating novel analgesic mechanisms with potentially reduced abuse liability, applicable in both in vitro binding assays and in vivo behavioral models.
Molekulargewicht:
410.98
Formel:
C25H31ClN2O
Target-Kategorie:
Dopamine Receptor,Opioid Receptor
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
