Compound 6h (Anticancer Agent 139) is a potent tubulin-binding small molecule, engaging Lys352 via pi-cation interaction. It demonstrates high growth inhibition in SNB-19, OVCAR-8, and NCI-H460 cells, with broader moderate activity across multiple other cancer cell lines, supporting its use in anticancer mechanism and cytotoxicity studies.
Molekulargewicht:
319.28
Formel:
C16H12F3N3O
Target-Kategorie:
Microtubule Associated,Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
