WS-383 is a potent and selective small molecule inhibitor of the DCN1-UBC12 protein-protein interaction, exhibiting reversible binding with an IC50 of 11 nM. It serves as a valuable chemical probe for studying cullin neddylation in biochemical and cellular assays, with utility in cancer and developmental biology research.
Molekulargewicht:
498.46
Reinheit:
98.80% (May vary between batches)
CAS Nummer:
[2247544-02-9]
Formel:
C18H21Cl2N9S2
Target-Kategorie:
E1/E2/E3 Enzyme
Anwendungsbeschreibung:
Solubility: DMSO:6.5 mg/mL (13.04 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten