TNFSF9 Antibody - C-terminal region

Artikelnummer: ASB-ARP61434_P050
Artikelname: TNFSF9 Antibody - C-terminal region
Artikelnummer: ASB-ARP61434_P050
Hersteller Artikelnummer: ARP61434_P050
Alternativnummer: ASB-ARP61434_P050-25UL,ASB-ARP61434_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Human
Alternative Synonym: CD137L, TNLG5A, 4-1BB-L
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 28kDa
NCBI: 8744
UniProt: P41273
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-TNFSF9 antibody
Catalog Number: ARP61434
Formalin Fixed Paraffin Embedded Tissue: Human Kidney
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec
WB Suggested Anti-TNFSF9 Antibody
Titration: 1.0 ug/ml
Positive Control: HepG2 Whole Cell
TNFSF9 antibody - C-terminal region (ARP61434_P050) in Human HepG2 using Western Blot