MOS, CT (Proto-oncogene Serine/threonine-protein Kinase Mos, MGC119962, MGC119963, MSV, Oocyte Maturation Factor Mos, Proto-oncogene c-Mos), Rabbit
Catalog Number:
USB-M4676-02C
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| Article Name: | MOS, CT (Proto-oncogene Serine/threonine-protein Kinase Mos, MGC119962, MGC119963, MSV, Oocyte Maturation Factor Mos, Proto-oncogene c-Mos), Rabbit |
| Biozol Catalog Number: | USB-M4676-02C |
| Supplier Catalog Number: | M4676-02C |
| Alternative Catalog Number: | USB-M4676-02C-200 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IHC |
| Immunogen: | Synthetic peptide selected from the C-terminal region of human MOS (KLH). |
| Mos, the c-mos protooncogene product, is a key regulator of meiosis in vertebrates. MOS is a 39kDa proto oncogene (c-Mos) encoded protein serine/threonine kinase. MOS is a monomeric protein that indirectly activates MAP kinase (Erk1/2) by directly phosphorylating MAP kinase kinase (Mck, MAPKK, MKK). MOS is known as a cytostatic factor (CSF) and is also thought to arrest unfertilized amphibian and mammalian cells during M phase, thus regulating oocyte maturation. MOS is destroyed before fertilisation, after exit from meiosis II, making it a good marker for studies of eggs during oogenesis and maturation. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Immunohistochemistry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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