Extracellular signal-regulated kinase 4 (ERK4) is a serine/threonine protein kinase also known as mitogen-activated protein kinase 4 (MAPK4), p63MAPK, and ERK3-related kinase. ERK4 and the structurally similar ERK3 (MAPK6) lack the phosphoacceptor sequence T-X-Y present in other MAPKs. ERK4 complexes with ERK3 to activate MAPK-activated protein kinase 5 (MK5), also known as PRAK. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
